Menopause and perimenopause are still baffling to most doctors, leaving patients exasperated as they grapple with symptoms ranging from hot flashes to insomnia to brain fog. As a leading neuroscientist and women's brain health specialist, Dr Mosconi unravels these mysteries by revealing how menopause doesn't just impact the ovaries - it's a hormonal show in which the brain takes centre stage. The decline of the hormone estrogen during menopause influences everything from body temperature to mood to memory, potentially paving the way for cognitive decline later in life. To conquer these challenges successfully, Mosconi brings us the latest approaches - explaining the role of cutting-edge hormone replacement therapies like 'designer estrogens,' hormonal contraception and key lifestyle changes encompassing diet, exercise, and self-care.